Dr. Dr Manikandan Velayutham

Assistant Professor · Department of Medicalbiotechnology and integrative physiology

Saveetha school of engineering

Author

APID

5482

ORCID

https://orcid.org/my-orcid?orcid=0000-00

Google Scholar

https://scholar.google.com/citations?user=-oAnOFoAAAAJ&hl=en

Location

Chennai, Tamil Nadu, India

Expertise

1. Drug discovery; 2. Bioactive potential of peptides; 3. Oxidative stress model; 4. Synthesis of Nanoparticle; 5. Zebrafish Model; 6. Anticancer; 7. Microbial Diversity; 8. Toxicology;

Areas of interest

1. Drug discovery; 2. Bioactive potential of peptides; 3. Oxidative stress model; 4. Synthesis of Nanoparticle; 5. Zebrafish Model; 6. Anticancer; 7. Microbial Diversity; 8. Toxicology;

Member since

January 2024

Biography

Dr. V. Manikandan assumed the position of Assistant Professor in the Department of Medical Biotechnology and Integrative Physiology in December 2022, bringing with him a wealth of academic achievements and research contributions.
Dr. Manikandan's contributions extend beyond the laboratory, as evidenced by his prolific publication record. He has authored and co-authored 19 papers published in esteemed national and international journals. The cumulative impact factor of his publications stands at an impressive 104.912, reflecting the quality and significance of his research. Furthermore, his work has been cited 348 times, attesting to the widespread recognition and influence of his findings, as indicated by his H index of 10.
Beyond his research acumen, Dr. Manikandan has accumulated 1.5 years of combined teaching and research experience.
The focal point of Dr. Manikandan's research lies in the characterization of peptide properties, toxicity assessments, and the exploration of bioactive molecules sourced from various origins. His work delves into the intricate details of these molecules, particularly their antioxidant and anti-cancer activities. By unraveling the potential therapeutic applications of peptides and bioactive molecules, Dr. Manikandan contributes significantly to the evolving landscape of medical biotechnology and integrative physiology.

Publications

1. Aquatic Peptide: The Potential Anti-Cancer and Anti-Microbial Activity of GE18 Derived from Pathogenic Fungus Aphanomyces invadans
2. Nimbin (N1) and analog N3 from the neem seeds suppress the migration of osteosarcoma MG-63 cells and arrest the cells in a quiescent state mediated via activation of the caspase-modulated apoptotic pathway
3. Nimbin analog N2 alleviates high testosterone induced oxidative stress in CHO cells and alters the expression of Tox3 and Dennd1a signal transduction pathway involved in the PCOS zebrafish
4. PS9, Derived from an Aquatic Fungus Virulent Protein, Glycosyl Hydrolase, Arrests MCF-7 Proliferation by Regulating Intracellular Reactive Oxygen Species and Apoptotic Pathways
5. Syringol, a wildfire residual methoxyphenol causes cytotoxicity and teratogenicity in zebrafish model
6. Trimetazidine with an adjuvant therapy to normalize the circulating visfatin concentration: future perspective and mechanistic strategies.